Suppression of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Function in Thalamocortical Neurons Prevents Genetically Determined and Pharmacologically Induced Absence Seizures

Suppression of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Function in Thalamocortical Neurons Prevents Genetically Determined and Pharmacologically Induced Absence Seizures

François David, Nihan Çarçak, Szabina Furdan, Filiz Onat, Timothy Gould, Ádám Mészáros, Giuseppe Di Giovanni, Vivian M. Hernández, C. Savio Chan, Magor L. Lőrincz, Vincenzo Crunelli

J Neurosci. 2018 Jul 25; 38(30): 6615–6627. doi: 10.1523/JNEUROSCI.0896-17.2018

PMCID: PMC6067077