Large Scale AAV Production with proprietary BAC-TO-AAV Technology
Adeno-associated viruses (AAVs), from the parvovirus family, are small viruses (22 nm) that are replication-defective, non-enveloped, non-pathogenic, and with a genome of single stranded DNA.
Most people treated with AAV will not build an immune response to remove the virus and the cells that have been successfully transduced by it.
Gene therapy vectors using AAV can infect both dividing and non-dividing cells and persist in an extrachromosomal state without integrating into the genome of the host cell.
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