Large Scale AAV Production with proprietary BAC-TO-AAV Technology

Adeno-associated viruses (AAVs), from the parvovirus family, are small viruses (22 nm) that are replication-defective, non-enveloped, non-pathogenic, and with a genome of single stranded DNA.

Most people treated with AAV will not build an immune response to remove the virus and the cells that have been successfully transduced by it.

Gene therapy vectors using AAV can infect both dividing and non-dividing cells and persist in an extrachromosomal state without integrating into the genome of the host cell.

Directly order your custom AAV, pre-made AAV, and a wide range of intermediate products online.

Custom AAV

Vector Production Service from 1E+13vg to 1E+17vg scale in 6+ weeks

Pre-Made AAV

Off-the shelf, immediate dispatchment, approx. default titer of 2E+13vg

HEK293

Custom AAVs in HEK293 system, from 1E+12vg to 2E+13vg

Plasmids

30ug starting at $350

Bacmids

DNA generation and pre-made bacmids with optional large-scale purification

Recombinant Baculovirus

To infect Sf9 insect cells as an intermediate step in AAV production

Lentivirus

Lentivirus packaging from 1E+8 TU to 1E+12 TU