For decades, Virovek has been a world leader in gene therapy and vector manufacturing.

Virovek offers custom AAV production services in Sf9 and HEK293, lentivirus and adenovirus packaging services, gene cloning services, recombinant baculoviruses, plasmid and bacmid DNA, quality control assays, and GLP manufacturing capabilities.

Virovek boasts the world’s most efficient large-scale AAV production system, capable of quickly and easily generating AAV with titers up to 1E+17 vg/mL. Prices start at $3,850 for 1E+13 vg of custom AAV.

 

Partners & Customers

Virovek has collaborated with over 100 world-class universities, non-profit institutions and industry pioneers to deliver gene therapy applications for tomorrow.
Genentech
Mount Sinai
UCSF
Charles river
BioMarin Pharmaceutical
Arup laboratories
https://www.nih.gov/
https://www.mit.edu/
https://www.tenayatherapeutics.com/
http://med.stanford.edu/
https://burke.weill.cornell.edu/
https://www.ku.dk/english/
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AAV Serotype

Retina

Heart

Liver

Lung

CNS/Brain

Skeletal Muscle

Other

AAV1

X

X

AAV2

X

X

AAV2-Retro

X

AAV3A, 3B

X

AAV4

X

X

AAV5

X

X

Immune system

AAV6

X

X

X

Immune system, pancreas

AAV7

X

X

X

AAV8

X

X

X

AAV9

X

X

AAVShH10

X

AAVrh10

X

X

X

AAV7m8

X

AAVDJ

X

X

X

Kidney, cervix, ovary, skin, fibroblast

AAVphp.b

X

AAVphp.eb

X

AAV10

X

X

X

X

kidney, uterus

AAV11

X

X

X

kidney, spleen, stomach

Serotype 2 generally tranduces cells more effectively in vitro than other serotypes

All other serotypes transduce cells more effectively in vivo

BAC-to-AAV

The World’s Most Efficient Large-Scale AAV Manufacturing System

Virovek’s patented BAC-TO-AAV technology has the capability of generating over 1E+16vg of adeno-associated virus in a single run. Learn more about our technology platform and explore a wide range of applications.

All AAV-Related Specialties and Services

Custom AAV

Vector production service from 1E+13vg to 1E+17vg scale in 6+ weeks

Pre-Made AAV

Off-the shelf, immediate dispatchment, approx. default titer of 2E+13vg

HEK293

Custom AAVs in HEK293 system, from 1E+12vg to 1E+15vg

Plasmids

30ug starting at $350

Bacmids

DNA generation and pre-made bacmids with optional large-scale purification

Lentivirus

Lentivirus packaging from 1E+8 TU to 1E+12 TU

Recombinant Baculovirus

To infect Sf9 insect cells as an intermediate step in AAV production

Gene Cloning

Single-step or complex cloning strategies tailored to your needs

Quality Control Assays

A wide selection of QC assays for your AAV products